AOD-9604 is a modified fragment of human growth hormone (hGH) that has been studied for its metabolic effects, particularly fat oxidation and lipolysis. As a research peptide, AOD-9604 is of interest to scientists studying obesity, metabolic syndrome, and exercise physiology. This article examines its research applications and the importance of sourcing from reliable peptides raw material manufacturers.
What Is AOD-9604?
AOD-9604 is a synthetic peptide consisting of amino acids 177-191 of human growth hormone, with a specific modification to enhance stability and activity. Unlike full-length growth hormone, AOD-9604 is designed to retain the lipolytic (fat-burning) properties of hGH without its growthpromoting effects.
Mechanism of Action
AOD-9604 exerts its effects through:
– Lipolysis Stimulation : Promotes the breakdown of stored fat (triglycerides) into free fatty acids.
– Inhibition of Lipogenesis : Reduces the formation of new fat cells.
– Metabolic Rate Enhancement : Increases energy expenditure and thermogenesis.
– Insulin Sensitivity Improvement : May enhance glucose metabolism.
Research Applications
AOD-9604 is utilized in laboratory settings for:
– Obesity and weight management research.
– Metabolic syndrome and insulin resistance studies.
– Exercise physiology and performance research.
– Lipid metabolism and energy homeostasis studies.
Regulatory Status
AOD-9604 is not FDA-approved for any indication and is designated as a research-use-only compound. It has not been evaluated by the FDA’s Pharmacy Compounding Advisory Committee (PCAC) as of 2026.
Research Findings
Preclinical studies and some human trials have suggested:
– Significant reduction in body fat in animal models.
– Improved lipid profiles in metabolic syndrome models.
– Potential for use as an adjunct to exercise in obesity research.
Sourcing AOD-9604 for Research
When sourcing AOD-9604 from peptide raw material suppliers, verify:
– HPLC Purity : ≥98% with batch-specific chromatograms.
– Mass Confirmation : Verification of the correct molecular weight (approximately 2,158 Da).
– Endotoxin Testing : Essential for in-vivo studies.
Quality Considerations
AOD-9604’s 15-amino-acid sequence requires careful synthesis and purification. Look for peptide raw material suppliers who provide:
– Batch-specific COAs with full analytical data.
– Stability studies under recommended storage conditions.
– Third-party testing options.
Product Disclaimer & Terms of Use
IMPORTANT NOTICE: FOR RESEARCH USE ONLY (RUO)
This product is intended exclusively for laboratory research and scientific development purposes. It is NOT a drug, food, medical device, cosmetic, or diagnostic product.